Publications

For all of our publications please visit our Google Scholar profile.

Schmidt lab publications

Mikhova M, Heyza JR, Meek K, Schmidt JC. 2023 “Single-molecule imaging reveals the kinetics of non-homologues end-joining in living cells”. bioRxiv, doi: https://doi.org/10.1101/2023.06.22.546088

Heyza JR*, Mikhova M*, Schmidt JC. 2023 . “Live Cell Single-Molecule Imaging to Study DNA Repair in Human Cells”. (Review) DNA Repair, 103540 *equal contribution

Brambati A, Sacco O*, Porcella S*, Heyza JR*, Kareh M, Schmidt JC, Sfeir A. 2023 “RHINO directs MMEJ to repair DNA breaks in mitosis”, Science. 10.1126/science.adh3694 *equal contribution

Heyza JR, Mikhova M, Bahl A, Broadbent DG, Schmidt JC. 2023 “Systematic analysis of the molecular and biophysical properties of key DNA damage response factors”. eLife, doi:12.10.7554/eLife.87086

Klump BS, Perez GI, Patrick EM, Adams-Boone K, Cohen SB, Han L, Yu K, Schmidt JC. 2023 “TCAB1 prevents nucleolar accumulation of the telomerase RNA to facilitate telomerase assembly”. Cell Reports, doi:10.1016/j.celrep.2023.112577

Broadbent DG*, Barnaba C*, Schmidt JC. 2023 “Quantitative analysis of autophagy reveals the role of ATG9 and ATG2 in autophagosome formation”. Journal of Cell Biology, https://doi.org/10.1083/jcb.202210078 *equal contribution
Highlighted in “Toward a standard model for autophagosome biogenesis” and “Tracking the transition from an ATG9A vesicle to an autophagosome”

Patrick EM, Slivka J, Payne B, Comstock MJ*, Schmidt JC*. 2020 “Observation of processive telomerase catalysis using high-resolution optical tweezers”. Nat. Chem. Biol. DOI: 10.1038/s41589-020-0478-0. *co-corresponding authors

Jens Postdoc publications

Youmans DT, Schmidt JC, Cech TR. 2018 "Live-cell imaging reveals the dynamics of PRC2 and recruitment to chromatin by SUZ12-associated subunits". Genes Dev. 32(11-12):794-805.

Schmidt JC, Zaug AJ, Kufer R, Cech TR. 2018 “Dynamics of human telomerase recruitment depend on template-telomere base-pairing”. Mol. Biol. Cell  mbc.E17-110637v1-mbc.E17-11-0637.

Schmidt JC, Zaug AJ, Cech TR. 2016 “Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres”. Cell. 2016 Aug 10. DOI: 10.1016/j.cell.2016.07.033.

Shukla S, Schmidt JC, Goldfarb KC, Cech TR, Parker R. 2016 “Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects”. Nat Struct Mol Biol. 23, 286-292.

Xi L*, Schmidt JC*, Zaug AJ, Ascarrunz DR, Cech TR. 2015 “A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression”. Genome Biology. 2015 Nov 10;16:231. *equal contribution

Schmidt JC, Cech TR. 2015 “Human telomerase: biogenesis, trafficking, recruitment, and activation”. Genes Dev. 29(11):1095-105.

Schmidt JC*, Dalby AB*, Cech TR. 2014 “Identification of human TERT elements necessary for telomerase recruitment to telomeres”. Elife. Oct 1;3. DOI: 10.7554/eLife.03563. *equal contribution

Jens PHD publications

Boeszoermenyi A, Schmidt JC, Cheeseman IM, Oberer M, Wagner G, Arthanari H. 2014 “Resonance assignments of the microtubule-binding domain of the C. elegans spindle and kinetochore-associated protein 1”. Biomol NMR Assign. 8:275-8.

Schmidt JC, Arthanari H, Boeszoermenyi A, Dashkevich NM, Wilson-Kubalek E, Monnier N, Markus M, Oberer M, Milligan RA, Bathe M, Wagner G, Grishchuk EL, Cheeseman IM. 2012 “The kinetochore-bound Ska1 complex tracks depolymerizing microtubules and binds to curved protofilaments”. Developmental Cell. 23:968-80.

Schmidt JC, Cheeseman IM. 2011 “Chromosome segregation: keeping kinetochores in the loop”. Current Biology 21:R110.

Schmidt JC, Kiyomitsu T, Hori T, Backer CB, Fukagawa T, Cheeseman IM. 2010 “Aurora B kinase controls the targeting of the Astrin-SKAP complex to bioriented kinetochores”. Journal of Cell Biology 191:269.

Jens Undergraduate publications

Evans ML, Schmidt JC, Ilbert M, Doyle SM, Quan S, Bardwell JC, Jakob U, Wickner S, Chapman MR. 2011 “E. coli chaperones DnaK, Hsp33 and Spy inhibit bacterial functional amyloid assembly”. Prion. 5:4, 323-334.

Hammer ND, Schmidt JC, Chapman MR. 2007 “The curli nucleator protein, CsgB, contains an amyloidogenic domain that directs CsgA polymerization”. Proc Natl Acad Sci U S A. 104:12494-9.